Genmab is building a deep pipeline of fully human antibody products to maximize its opportunities for success. We have seven products in clinical trials and have the financial flexibility needed to move our products forward. Genmab has chosen to focus on products to treat various cancers, where human antibodies are expected to be particularly useful as they should lend themselves to long-term therapy without the risk of rejection by the body's immune system. Furthermore, Genmab is evaluating a large number of interesting disease targets for future product development.
TitleIndicationsDevelopment StatusOur Rights
Arzerra (ofatumumab)
Chronic lymphocytic leukemia (CLL)Phase IIIWorldwide in collaboration with GlaxoSmithKline (GSK)
CLL front line w/chlorambucilPhase IIIWorldwide in collaboration with GSK
Non-Hodgkin’s lymphoma (NHL)Phase IIIWorldwide in collaboration with GSK
Rheumatoid Arthritis (RA) - methotrexate ref.Phase IIIWorldwide in collaboration with GSK
RA - TNF-alpha ref.Phase IIIWorldwide in collaboration with GSK
CLL front line w/FCPhase IIWorldwide in collaboration with GSK
NHL front line w/CHOPPhase IIWorldwide in collaboration with GSK
Diffuse large B-cell lymphoma (DLBCL)Phase IIWorldwide in collaboration with GSK
Relapsing remitting multiple sclerosis (RRMS)Phase IIWorldwide in collaboration with GSK
RA - subcutaneousPhase I/IIWorldwide in collaboration with GSK
NHL/CLL in JapanPhase IWorldwide in collaboration with GSK
Zalutumumab (HuMax-EGFr)
Head and neck cancerPhase IIIWorldwide
Head and neck cancer front line w/radiotherapyPhase IIIWorldwide
Head and neck cancer front line w/chemo-radiationPhase I/IIWorldwide
Head and neck cancer w/radiotherapyPhase I/IIWorldwide
R1507
SarcomaPhase IIWorldwide in collaboration with Roche
HuMax-CD38
Multiple MyelomaPhase I/IIWorldwide
R1671
AsthmaPhase IWorldwide in collaboration with Roche
R1512
Peripheral vascular diseasePhase IWorldwide in collaboration with Roche
R4930
AsthmaPhase IWorldwide in collaboration with Roche
HuMax-HepC
Hepatitis CPre-clinicalWorldwide
HuMax-TAC
Organ transplant rejectionPre-clinicalWorldwide
HuMax-CD32b
CancerPre-clinicalWorldwide